TREND Community’s Report on Understanding Pain and Its Impact on Mental Health in Fabry Disease using Real-World Evidence From Social Media

Picture of Maria Picone
Maria Picone

PHILADELPHIA, February 22, 2023 – TREND Community, a digital health analytics company that turns the conversations of rare, chronic, and emerging disease communities into actionable insights today announced that its poster, titled “Understanding Pain and Its Impact on Mental Health in Fabry Disease using Real-World Evidence From Social Media,” will be presented at the 19th Annual WORLDSymposium™ Research Meeting to be held February 22–26, 2023 in Orlando, Florida.

The poster is based on a study that leveraged TREND’s analysis of over 96,000 posts across a private Facebook group dedicated to Fabry disease.

TREND’s proprietary analytics engine, which incorporates artificial intelligence (AI) and natural language processing (NLP), evaluated the possible impact on the mental health of Fabry disease and the possible symptoms that may heighten these impacts. These results demonstrate the connection between the physical symptoms of Fabry disease and negative mental health impacts with the strongest relationship between the symptom of pain and mental health.

For the poster and complete abstract, please use this link.

The authors are Maria Picone, Maurice Fleurie, Enming Zhang, Monica Converse, Rachelle Cook, Wei Li, E. Robert Wassman, and Christopher DeFelice.

This work was funded by Chiesi Global Rare Disease.

For additional information about this poster or collaboration and partnerships with TREND, please contact: Maria Picone,

About TREND Community
TREND Community turns the conversations of people who have rare, chronic, and emerging diseases and their caregivers/care partners into actionable insights through our proprietary evidence-accelerator approach. Above all, we prioritize the privacy and trust of every community member. For more information visit

About Chiesi Global Rare Disease
Chiesi Global Rare Diseases is a business unit of the Chiesi Group established to deliver innovative therapies and solutions for people affected by rare diseases. As a family business, Chiesi Group strives to create a world where it is common to have a therapy for all diseases and acts as a force for good, for society and the planet. The goal of the Global Rare Diseases unit is to ensure equal access so as many people as possible can experience their most fulfilling life. The unit collaborates with the rare disease community around the globe to bring voice to underserved people in the health care system. For more information visit